The I.S.T. rotary manifold with integrated dry break coupling ensures continuous functional safety and crossover protection in product separation: there is an automatic check whether the coupling is closed properly - only then the product flow is released. Additional isolation valves are not necessary. The advantage: the self-controlled system guarantees convenient and operationally reliable protection against faulty switching, faulty operation, product mixture or loss and admission of air. Product leakages are even avoided at the noncoupled connections which are under product flow. The flow direction and pressure do not influence the function.